Osteoradionecrosis
What is osteoradionecrosis?
Osteoradionecrosis is an irradiated bone (undergo radiotherapy) that becomes devitalized(dead) and exposed through the overlying skin or mucosa, without healing for 3 months. It is more common in mandible (your lower jaw) compared to your maxilla (the upper jaw)Â due to its compact structure and it receives less blood supply compared to the maxilla. Continue reading
Hemoglobin is the protein found in red blood cells in our blood that is responsible for carrying oxygen to all the different parts of out body. Hemoglobin is made up of 4 protein chains, ie 2 beta globin and 2 alpha globin. Thalassemia occurs when there is decrease in production or absence of production of either of these chains, leading to malfunctioning hemoglobins that are unable to carry oxygen. This then leads to anemia.
Thalassemia is thus classified by the type of globin that is affected: either alpha thalassemia or beta thalassemia, and each is classified according to the severity of which one is affected, ie either thalassemia major or thalassemia minor. People with thalassemia minor, either alpha or beta, may not have any symptoms. Continue reading
Osteoradionecrosis (ORN) is a condition of nonvital bone in a site of radiation injury. ORN can be spontaneous, but it most commonly results from tissue injury. The absence of reserve reparative capacity is a result of the prior radiation injury. Even apparently innocuous forms of trauma such as denture-related injury, ulcers, or tooth extraction can overwhelm the reparative capacity of the radiation-injured bone. Continue reading